Cargando…

Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis

Podosomes are compartmentalized actin-rich adhesions, defined by their ability to locally secrete proteases and remodel extracellular matrix. Matrix remodeling by endothelial podosomes facilitates invasion and thereby vessel formation. However, the mechanisms underlying endothelial podosome formatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Collins, Kerrie B., Kang, Hojin, Matsche, Jacob, Klomp, Jennifer E., Rehman, Jalees, Malik, Asrar B., Karginov, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041690/
https://www.ncbi.nlm.nih.gov/pubmed/31865373
http://dx.doi.org/10.1083/jcb.201903023

Ejemplares similares