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Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis
Podosomes are compartmentalized actin-rich adhesions, defined by their ability to locally secrete proteases and remodel extracellular matrix. Matrix remodeling by endothelial podosomes facilitates invasion and thereby vessel formation. However, the mechanisms underlying endothelial podosome formatio...
Autores principales: | Collins, Kerrie B., Kang, Hojin, Matsche, Jacob, Klomp, Jennifer E., Rehman, Jalees, Malik, Asrar B., Karginov, Andrei V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041690/ https://www.ncbi.nlm.nih.gov/pubmed/31865373 http://dx.doi.org/10.1083/jcb.201903023 |
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