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TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis

Myeloid-derived suppressor cells (MDSCs) are “polarized” myeloid cells that effectively promote tumorigenesis by inhibiting antitumor immunity. How myeloid cells acquire the protumoral properties during tumorigenesis is poorly understood. We report here that the polarity protein TIPE2 (tumor necrosi...

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Detalles Bibliográficos
Autores principales:	Yan, Dehong, Wang, Jinghui, Sun, Honghong, Zamani, Ali, Zhang, Honglin, Chen, Weihong, Tang, Aifa, Ruan, Qingguo, Yang, Xiaolu, Chen, Youhai H., Wan, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041705/ https://www.ncbi.nlm.nih.gov/pubmed/31662347 http://dx.doi.org/10.1084/jem.20182005

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