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Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge
We previously generated a panel of human monoclonal antibodies (mAbs) against Zika virus (ZIKV) and identified one, ZIKV-116, that shares germline usage with mAbs identified in multiple donors. Here we show that ZIKV-116 interferes with ZIKV infection at a post-cellular attachment step by blocking v...
Autores principales: | Zhao, Haiyan, Xu, Lily, Bombardi, Robin, Nargi, Rachel, Deng, Zengqin, Errico, John M., Nelson, Christopher A., Dowd, Kimberly A., Pierson, Theodore C., Crowe, James E., Diamond, Michael S., Fremont, Daved H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041715/ https://www.ncbi.nlm.nih.gov/pubmed/31757867 http://dx.doi.org/10.1084/jem.20191792 |
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