Cargando…

UBE2M promotes cell proliferation via the β-catenin/cyclin D1 signaling in hepatocellular carcinoma

Upregulated ubiquitin-conjugating enzyme E2M (UBE2M) is associated with poor prognosis in malignancies; However, the phenotype and mechanism of action of UBE2M in hepatocellular carcinoma (HCC) remain elusive. Here, we report that UBE2M is overexpressed and correlated with poor prognosis in HCC pati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Guang-Cong, Yu, Xiang-Nan, Sun, Jia-Lei, Xiong, Ju, Yang, Yi-Jun, Jiang, Xue-Mei, Zhu, Ji-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041726/ https://www.ncbi.nlm.nih.gov/pubmed/32012120 http://dx.doi.org/10.18632/aging.102749

Ejemplares similares

UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma
por: Liu, Li-Li, et al.
Publicado: (2019)

The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression
por: Ho, Nicole Pui Yu, et al.
Publicado: (2021)

UBE2T promotes β‐catenin nuclear translocation in hepatocellular carcinoma through MAPK/ERK‐dependent activation
por: Lioulia, Elisavet, et al.
Publicado: (2022)

UBE3C Promotes Growth and Metastasis of Renal Cell Carcinoma via Activating Wnt/β-Catenin Pathway
por: Wen, Ji Ling, et al.
Publicado: (2015)

UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway
por: Hu, Wei, et al.
Publicado: (2016)

UBE2T-mediated Akt ubiquitination and Akt/β-catenin activation promotes hepatocellular carcinoma development by increasing pyrimidine metabolism
por: Zhu, Zhenru, et al.
Publicado: (2022)

UBE2C affects breast cancer proliferation through the AKT/mTOR signaling pathway
por: Lu, Zi-Nan, et al.
Publicado: (2021)

Expression of beta-catenin in hepatocellular carcinoma in relation to tumor cell proliferation and cyclin D1 expression.
por: Joo, Mee, et al.
Publicado: (2003)

Overexpression of UBE2M through Wnt/β-Catenin signaling is associated with poor prognosis and chemotherapy resistance in colorectal cancer
por: Xu, Jianmin, et al.
Publicado: (2020)

Luteolin-7-glucoside Promotes Human Epidermal Stem Cell Proliferation by Upregulating β-Catenin, c-Myc, and Cyclin Expression
por: Wan, Dapeng, et al.
Publicado: (2019)

Oncogenic UBE3C promotes breast cancer progression by activating Wnt/β-catenin signaling
por: Hang, Chen, et al.
Publicado: (2021)

UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway
por: Wang, Yang, et al.
Publicado: (2023)

Pre-mRNA processing factor 19 functions in DNA damage repair and radioresistance by modulating cyclin D1 in hepatocellular carcinoma
por: Yu, Xiang-Nan, et al.
Publicado: (2021)

UBE2O promotes hepatocellular carcinoma cell proliferation and invasion by regulating the AMPKα2/mTOR pathway
por: Shi, Zhan, et al.
Publicado: (2021)

Ube2s-stabilized β-catenin protects against myocardial ischemia/reperfusion injury by activating HIF-1α signaling
por: Chen, Xi, et al.
Publicado: (2020)

Ube2S regulates Wnt/β-catenin signaling and promotes the progression of non-small cell lung cancer
por: Qin, Yanan, et al.
Publicado: (2020)

UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway
por: Hu, Wenjing, et al.
Publicado: (2021)

NOP7 interacts with β-catenin and activates β-catenin/TCF signaling in hepatocellular carcinoma cells
por: Wu, Nan, et al.
Publicado: (2018)

Heat shock protein 70 downregulation inhibits proliferation, migration and tumorigenicity in hepatocellular carcinoma cells
por: Xiong, Ju, et al.
Publicado: (2017)

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer
por: Peng, Shengmeng, et al.
Publicado: (2022)

Cyclin K interacts with β-catenin to induce Cyclin D1 expression and facilitates tumorigenesis and radioresistance in lung cancer
por: Yao, Guojun, et al.
Publicado: (2020)

MUC1 regulates cyclin D1 gene expression through p120 catenin and β-catenin
por: Liu, X, et al.
Publicado: (2014)

UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells
por: Xiong, Yu, et al.
Publicado: (2019)

URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway
por: Liu, Yayun, et al.
Publicado: (2020)

SNF2H promotes hepatocellular carcinoma proliferation by activating the Wnt/β-catenin signaling pathway
por: Wang, Yanan, et al.
Publicado: (2016)

Downregulation of miR-432 activates Wnt/β-catenin signaling and promotes human hepatocellular carcinoma proliferation
por: Jiang, Nan, et al.
Publicado: (2015)

Psoralen promotes the expression of cyclin D1 in chondrocytes via the Wnt/β-catenin signaling pathway
por: Zheng, Wenwei, et al.
Publicado: (2017)

Ube2s stabilizes β-Catenin through K11-linked polyubiquitination to promote mesendoderm specification and colorectal cancer development
por: Li, Zhaoyan, et al.
Publicado: (2018)

β-catenin activated hepatocellular adenoma
por: Chu, Hyun Hee, et al.
Publicado: (2013)

β-Catenin signaling in hepatocellular carcinoma
por: Xu, Chuanrui, et al.
Publicado: (2022)

Cyclin G2 Suppresses Estrogen-Mediated Osteogenesis through Inhibition of Wnt/β-Catenin Signaling
por: Gao, Jinlan, et al.
Publicado: (2014)

A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination
por: Yu, Zeyuan, et al.
Publicado: (2020)

CyclinD1 protein expressed in pterygia is associated with β-catenin protein localization
por: Tung, Jai-Nien, et al.
Publicado: (2010)

β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis
por: Mirando, Anthony J, et al.
Publicado: (2010)

Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells
por: Shi, Kaishun, et al.
Publicado: (2018)

The Overexpression of CARM1 Promotes Human Osteosarcoma Cell Proliferation through the pGSK3β/β-Catenin/cyclinD1 Signaling Pathway
por: Li, Shijie, et al.
Publicado: (2017)

β‐Catenin Accumulation and Mutation of Exon 3 of the β‐Catenin Gene in Hepatocellular Carcinoma
por: Kondo, Yutaka, et al.
Publicado: (1999)

Downregulation of miR-610 promotes proliferation and tumorigenicity and activates Wnt/β-catenin signaling in human hepatocellular carcinoma
por: Zeng, Xian-Cheng, et al.
Publicado: (2014)

The diagnostic and prognostic value of UBE2T in intrahepatic cholangiocarcinoma
por: Yu, Hua, et al.
Publicado: (2020)

UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells
por: Luo, Yanyan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a6s6at1r3mg6fmerrltm73g1jl