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TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a disease of aging. The TP53 gene product regulates cell growth, aging, and cancer. To determine the important targets of TP53 in PDAC, we examined the expression of 440 proteins on a reverse phase protein array (RPPA) in PDAC-derived MIA-PaCa-2 cells which...

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Detalles Bibliográficos
Autores principales:	Akula, Shaw M., Ruvolo, Peter P., McCubrey, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041729/ https://www.ncbi.nlm.nih.gov/pubmed/31986125 http://dx.doi.org/10.18632/aging.102776

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