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HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB

In this study, we investigated the role of heme oxygenase-1 (HO-1) in intervertebral disc degeneration (IDD) by assessing the effects of HO-1 overexpression on IL-1β-induced apoptosis in nucleus pulposus cells (NPCs). Immunohistochemical staining showed HO-1 expression to be lower in NPCs from IDD p...

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Detalles Bibliográficos
Autores principales:	Zou, Luetao, Lei, Hongyan, Shen, Jieliang, Liu, Xulin, Zhang, Xiang, Wu, Longxi, Hao, Jie, Jiang, Wei, Hu, Zhenming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041769/ https://www.ncbi.nlm.nih.gov/pubmed/32015215 http://dx.doi.org/10.18632/aging.102753

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