Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma

Purpose: F14512 is an epipodophyllotoxin derivative from etoposide, combined with a spermine moiety introduced as a cell delivery vector. The objective of this study was to compare the safety and antitumor activity of F14512 and etoposide phosphate in dogs with spontaneous non-Hodgkin lymphoma (NHL)...

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Detalles Bibliográficos
Autores principales: Boyé, Pierre, Floch, Franck, Serres, François, Segaoula, Zacharie, Hordeaux, Juliette, Pascal, Quentin, Coste, Virginie, Courapied, Sandy, Bouchaert, Emmanuel, Rybicka, Agata, Mazuy, Claire, Marescaux, Laurent, Geeraert, Kévyn, Fournel-Fleury, Corinne, Duhamel, Alain, Machuron, François, Ferré, Pierre, Pétain, Aurélie, Guilbaud, Nicolas, Tierny, Dominique, Gomes, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041934/
https://www.ncbi.nlm.nih.gov/pubmed/32133044
http://dx.doi.org/10.18632/oncotarget.27461

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