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DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR

Despite reductions in mortality from the use of highly active antiretroviral therapy (HAART), the presence of latent or transcriptionally silent proviruses prevents HIV cure/eradication. We have previously reported that DNA-dependent protein kinase (DNA-PK) facilitates HIV transcription by interacti...

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Detalles Bibliográficos
Autores principales: Zicari, Sonia, Sharma, Adhikarimayum Lakhikumar, Sahu, Geetaram, Dubrovsky, Larisa, Sun, Lin, Yue, Han, Jada, Tejaswi, Ochem, Alex, Simon, Gary, Bukrinsky, Michael, Tyagi, Mudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041937/
https://www.ncbi.nlm.nih.gov/pubmed/32133046
http://dx.doi.org/10.18632/oncotarget.27487