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DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR
Despite reductions in mortality from the use of highly active antiretroviral therapy (HAART), the presence of latent or transcriptionally silent proviruses prevents HIV cure/eradication. We have previously reported that DNA-dependent protein kinase (DNA-PK) facilitates HIV transcription by interacti...
Autores principales: | Zicari, Sonia, Sharma, Adhikarimayum Lakhikumar, Sahu, Geetaram, Dubrovsky, Larisa, Sun, Lin, Yue, Han, Jada, Tejaswi, Ochem, Alex, Simon, Gary, Bukrinsky, Michael, Tyagi, Mudit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041937/ https://www.ncbi.nlm.nih.gov/pubmed/32133046 http://dx.doi.org/10.18632/oncotarget.27487 |
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