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Differential regulation of sFlt-1 splicing by U2AF65 and JMJD6 in placental-derived and endothelial cells
Despite years of study, the gestational disorder preeclampsia (PE) remains poorly understood. One proposed mechanism of PE development is increased soluble VEGF receptor-1 (sFlt-1), ultimately causing angiogenic imbalance and endothelial dysfunction. The soluble protein is an alternative splice vari...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042122/ https://www.ncbi.nlm.nih.gov/pubmed/32039444 http://dx.doi.org/10.1042/BSR20193252 |