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Novel pathogenic alterations in pediatric and adult desmoid-type fibromatosis – A systematic analysis of 204 cases

Desmoid-type fibromatosis (DTF, aggressive fibromatosis) is a non-metastasizing mesenchymal neoplasm of deep soft tissue with a tendency towards local recurrence. Genetic alterations affecting canonical Wnt/β-catenin signaling are reported in the majority of DTF. While most sporadic DTF harbor somat...

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Detalles Bibliográficos
Autores principales: Trautmann, Marcel, Rehkämper, Jan, Gevensleben, Heidrun, Becker, Jessica, Wardelmann, Eva, Hartmann, Wolfgang, Grünewald, Inga, Huss, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042250/
https://www.ncbi.nlm.nih.gov/pubmed/32099073
http://dx.doi.org/10.1038/s41598-020-60237-6