Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen

Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, renal, gastrointestinal and liver injuries. The und...

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Detalles Bibliográficos
Autores principales: Tiwari, Shuchita, Mishra, Manish, Salemi, Michelle R., Phinney, Brett S., Newens, Joanne L., Gomes, Aldrin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042271/
https://www.ncbi.nlm.nih.gov/pubmed/32099006
http://dx.doi.org/10.1038/s41598-020-60053-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042271/
https://www.ncbi.nlm.nih.gov/pubmed/32099006
http://dx.doi.org/10.1038/s41598-020-60053-y

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