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Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen
Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, renal, gastrointestinal and liver injuries. The und...
Autores principales: | Tiwari, Shuchita, Mishra, Manish, Salemi, Michelle R., Phinney, Brett S., Newens, Joanne L., Gomes, Aldrin V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042271/ https://www.ncbi.nlm.nih.gov/pubmed/32099006 http://dx.doi.org/10.1038/s41598-020-60053-y |
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