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Increased mitochondrial and lipid metabolism is a conserved effect of Insulin/PI3K pathway downregulation in adipose tissue

The Insulin/IGF-1 signalling (IIS) pathway plays an essential role in the regulation of glucose and lipid homeostasis. At the same time, a reduction in the IIS pathway activity can extend lifespan and healthspan in various model organisms. Amongst a number of body organs that sense and respond to in...

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Detalles Bibliográficos
Autores principales:	Bettedi, Lucia, Yan, Anqi, Schuster, Eugene, Alic, Nazif, Foukas, Lazaros C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042323/ https://www.ncbi.nlm.nih.gov/pubmed/32099025 http://dx.doi.org/10.1038/s41598-020-60210-3

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