The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment

Nitric oxide (NO) shows great role in tumor biology. Recent years, more and more researches utilized NO donor in tumor targeting drug delivery and treatment. In this review, we summarized the NO donors by their endogenous and exogenous stimuli. Then the application of NO donors, which was the main a...

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Detalles Bibliográficos
Autores principales: Qin, Lin, Gao, Huile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042479/
https://www.ncbi.nlm.nih.gov/pubmed/32104467
http://dx.doi.org/10.1016/j.ajps.2018.10.005
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author Qin, Lin
Gao, Huile
author_facet Qin, Lin
Gao, Huile
author_sort Qin, Lin
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description Nitric oxide (NO) shows great role in tumor biology. Recent years, more and more researches utilized NO donor in tumor targeting drug delivery and treatment. In this review, we summarized the NO donors by their endogenous and exogenous stimuli. Then the application of NO donors, which was the main aim of the review, was discussed in detailed according to their functions, including inducing tumor cell apoptosis, reversing tumor multidrug resistance, inhibiting tumor metastasis and improving drug delivery.
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spelling pubmed-70424792020-02-26 The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment Qin, Lin Gao, Huile Asian J Pharm Sci Review Article Nitric oxide (NO) shows great role in tumor biology. Recent years, more and more researches utilized NO donor in tumor targeting drug delivery and treatment. In this review, we summarized the NO donors by their endogenous and exogenous stimuli. Then the application of NO donors, which was the main aim of the review, was discussed in detailed according to their functions, including inducing tumor cell apoptosis, reversing tumor multidrug resistance, inhibiting tumor metastasis and improving drug delivery. Shenyang Pharmaceutical University 2019-07 2018-11-22 /pmc/articles/PMC7042479/ /pubmed/32104467 http://dx.doi.org/10.1016/j.ajps.2018.10.005 Text en © 2018 Shenyang Pharmaceutical University. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Qin, Lin
Gao, Huile
The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
title The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
title_full The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
title_fullStr The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
title_full_unstemmed The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
title_short The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
title_sort application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042479/
https://www.ncbi.nlm.nih.gov/pubmed/32104467
http://dx.doi.org/10.1016/j.ajps.2018.10.005
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