Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer()

ESR1 mutations in breast cancer are known as one of the mechanisms of resistance to aromatase inhibitors. These mutations often occur in the hotspot regions in the ligand binding domain (LBD), but comprehensive mutational analysis has shown that mutations are observed throughout the whole LBD. We pr...

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Detalles Bibliográficos
Autores principales: Masunaga, Nanae, Kagara, Naofumi, Motooka, Daisuke, Nakamura, Shota, Miyake, Tomohiro, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042480/
https://www.ncbi.nlm.nih.gov/pubmed/32105989
http://dx.doi.org/10.1016/j.tranon.2019.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042480/
https://www.ncbi.nlm.nih.gov/pubmed/32105989
http://dx.doi.org/10.1016/j.tranon.2019.12.007

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