Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis

Low doses of antibiotics can trigger secondary metabolite biosynthesis in bacteria, but the underlying mechanisms are generally unknown. We sought to better understand this phenomenon by studying how the antibiotic trimethoprim activates the synthesis of the virulence factor malleilactone in Burkhol...

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Detalles Bibliográficos
Autores principales: Li, Anran, Mao, Dainan, Yoshimura, Aya, Rosen, Paul C., Martin, W. Lance, Gallant, Étienne, Wühr, Martin, Seyedsayamdost, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042699/
https://www.ncbi.nlm.nih.gov/pubmed/32098820
http://dx.doi.org/10.1128/mBio.03210-19

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