Cargando…

A brainstem-central amygdala circuit underlies defensive responses to learned threats

Norepinephrine (NE) plays a central role in the acquisition of aversive learning via actions in the lateral nucleus of the amygdala (LA) [1, 2]. However, the function of NE in expression of aversively-conditioned responses has not been established. Given the role of the central nucleus of the amygda...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Yiran, Piper, Walter T., Branigan, Lauren A., Vazey, Elena M., Aston-Jones, Gary, Lin, Longnian, LeDoux, Joseph E., Sears, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042728/ https://www.ncbi.nlm.nih.gov/pubmed/31758092 http://dx.doi.org/10.1038/s41380-019-0599-6

Ejemplares similares

Noradrenergic Regulation of Central Amygdala in Aversive Pavlovian-to-Instrumental Transfer
por: Campese, Vincent D., et al.
Publicado: (2017)

Modulation of instrumental responding by a conditioned threat stimulus requires lateral and central amygdala
por: Campese, Vincent D., et al.
Publicado: (2015)

Characterization of the amplificatory effect of norepinephrine in the acquisition of Pavlovian threat associations
por: Díaz-Mataix, Lorenzo, et al.
Publicado: (2017)

Active vs. reactive threat responding is associated with differential c-Fos expression in specific regions of amygdala and prefrontal cortex
por: Martinez, Raquel C.R., et al.
Publicado: (2013)

Temporally and anatomically specific contributions of the human amygdala to threat and safety learning
por: Wen, Zhenfu, et al.
Publicado: (2022)

Primary auditory cortex regulates threat memory specificity
por: Wigestrand, Mattis B., et al.
Publicado: (2017)

Lesions of lateral or central amygdala abolish aversive Pavlovian-to-instrumental transfer in rats
por: Campese, Vincent D., et al.
Publicado: (2014)

Intrinsic Circuits in the Lateral Central Amygdala
por: Hunt, Sarah, et al.
Publicado: (2017)

Heterogeneity in signaled active avoidance learning: substantive and methodological relevance of diversity in instrumental defensive responses to threat cues
por: Galatzer-Levy, Isaac R., et al.
Publicado: (2014)

Extended amygdala-parabrachial circuits alter threat assessment and regulate feeding
por: Luskin, Andrew T., et al.
Publicado: (2021)

Ultrastructural Characterization of Noradrenergic Axons and Beta-Adrenergic Receptors in the Lateral Nucleus of the Amygdala
por: Farb, Claudia R., et al.
Publicado: (2010)

Enhanced Synaptic Transmission in the Extended Amygdala and Altered Excitability in an Extended Amygdala to Brainstem Circuit in a Dravet Syndrome Mouse Model
por: Yan, Wen Wei, et al.
Publicado: (2021)

Neural defensive circuits underlie helping under threat in humans
por: Vieira, Joana B, et al.
Publicado: (2022)

Medial Amygdala Lesions Selectively Block Aversive Pavlovian–Instrumental Transfer in Rats
por: McCue, Margaret G., et al.
Publicado: (2014)

Neural substrates for expectation-modulated fear learning in the amygdala and periaqueductal gray
por: Johansen, Joshua P., et al.
Publicado: (2010)

Human threat circuits: Threats of pain, aggressive conspecific, and predator elicit distinct BOLD activations in the amygdala and hypothalamus
por: Bertram, Teresa, et al.
Publicado: (2023)

GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?
por: Cunha, Catarina, et al.
Publicado: (2010)

Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala
por: Samineni, Vijay K, et al.
Publicado: (2021)

The Amygdala Encodes Specific Sensory Features of an Aversive Reinforcer
por: Dębiec, Jacek, et al.
Publicado: (2010)

The role of the lateral amygdala in the retrieval and maintenance of fear-memories formed by repeated probabilistic reinforcement
por: Erlich, Jeffrey C., et al.
Publicado: (2012)

Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala
por: Ostroff, Linnaea E, et al.
Publicado: (2019)

Hebbian Reverberations in Emotional Memory Micro Circuits
por: Johnson, Luke R., et al.
Publicado: (2009)

Central amygdala micro-circuits mediate fear extinction
por: Whittle, Nigel, et al.
Publicado: (2021)

Motivational factors underlying aversive Pavlovian-instrumental transfer
por: Campese, Vinn D., et al.
Publicado: (2020)

Threat visibility modulates the defensive brain circuit underlying fear and anxiety
por: Rigoli, Francesco, et al.
Publicado: (2016)

The emerging role of norepinephrine in cognitive dysfunctions of Parkinson's disease
por: Vazey, Elena M., et al.
Publicado: (2012)

Beta-Adrenergic Receptors in the Lateral Nucleus of the Amygdala Contribute to the Acquisition but Not the Consolidation of Auditory Fear Conditioning
por: Bush, David E. A., et al.
Publicado: (2010)

Development of Threat Expression Following Infant Maltreatment: Infant and Adult Enhancement but Adolescent Attenuation
por: Junod, Anouchka, et al.
Publicado: (2019)

Experience-dependent modification of a central amygdala fear circuit
por: Li, Haohong, et al.
Publicado: (2013)

The paraventricular thalamus controls a central amygdala fear circuit
por: Penzo, Mario A., et al.
Publicado: (2015)

Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect
por: Griessner, Johannes, et al.
Publicado: (2018)

Regulation of the Fear Network by Mediators of Stress: Norepinephrine Alters the Balance between Cortical and Subcortical Afferent Excitation of the Lateral Amygdala
por: Johnson, Luke R., et al.
Publicado: (2011)

Threat vigilance and intrinsic amygdala connectivity
por: Kirk, Peter A., et al.
Publicado: (2022)

A central alarm system that gates multi-sensory innate threat cues to the amygdala
por: Kang, Sukjae J., et al.
Publicado: (2022)

A brainstem circuit for nausea suppression
por: Zhang, Chuchu, et al.
Publicado: (2022)

The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm
por: LeDoux, J E, et al.
Publicado: (2017)

Heterogeneity in threat extinction learning: substantive and methodological considerations for identifying individual difference in response to stress
por: Galatzer-Levy, Isaac R., et al.
Publicado: (2013)

Neural Circuit Mechanism Underlying the Feeding Controlled by Insula-Central Amygdala Pathway
por: Zhang-Molina, Calvin, et al.
Publicado: (2020)

General Anesthetics Activate a Potent Central Pain-Suppression Circuit in the Amygdala
por: Hua, Thuy, et al.
Publicado: (2020)

The Effect of Threat on Novelty Evoked Amygdala Responses
por: Balderston, Nicholas L., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cfd8aua2nu37c4njmmt41jmeeu