Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?

Sufficient uterine remodeling is essential for fetal survival and development. Pathologies related to poor remodeling have a negative impact on maternal and fetal health even years after birth. Research of the last decades yielded excellent studies demonstrating the key role of immune cells in the r...

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Detalles Bibliográficos
Autores principales: Meyer, Nicole, Zenclussen, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043066/
https://www.ncbi.nlm.nih.gov/pubmed/32140155
http://dx.doi.org/10.3389/fimmu.2020.00246
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author Meyer, Nicole
Zenclussen, Ana Claudia
author_facet Meyer, Nicole
Zenclussen, Ana Claudia
author_sort Meyer, Nicole
collection PubMed
description Sufficient uterine remodeling is essential for fetal survival and development. Pathologies related to poor remodeling have a negative impact on maternal and fetal health even years after birth. Research of the last decades yielded excellent studies demonstrating the key role of immune cells in the remodeling processes. This review summarizes the current knowledge about the relevance of immune cells for uterine remodeling during pregnancy and further discusses immunomodulatory effects of man-made endocrine disrupting chemicals on immune cells.
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spelling pubmed-70430662020-03-05 Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals? Meyer, Nicole Zenclussen, Ana Claudia Front Immunol Immunology Sufficient uterine remodeling is essential for fetal survival and development. Pathologies related to poor remodeling have a negative impact on maternal and fetal health even years after birth. Research of the last decades yielded excellent studies demonstrating the key role of immune cells in the remodeling processes. This review summarizes the current knowledge about the relevance of immune cells for uterine remodeling during pregnancy and further discusses immunomodulatory effects of man-made endocrine disrupting chemicals on immune cells. Frontiers Media S.A. 2020-02-19 /pmc/articles/PMC7043066/ /pubmed/32140155 http://dx.doi.org/10.3389/fimmu.2020.00246 Text en Copyright © 2020 Meyer and Zenclussen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Meyer, Nicole
Zenclussen, Ana Claudia
Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?
title Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?
title_full Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?
title_fullStr Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?
title_full_unstemmed Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?
title_short Immune Cells in the Uterine Remodeling: Are They the Target of Endocrine Disrupting Chemicals?
title_sort immune cells in the uterine remodeling: are they the target of endocrine disrupting chemicals?
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043066/
https://www.ncbi.nlm.nih.gov/pubmed/32140155
http://dx.doi.org/10.3389/fimmu.2020.00246
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