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Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy

A 22-year-old female presented with bilateral, progressive diminution of vision. Slit-lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad-based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM),...

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Detalles Bibliográficos
Autores principales: Ichhpujani, Parul, Kaushik, Sushmita, Gupta, Amit, Pandav, Surinder S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043171/
https://www.ncbi.nlm.nih.gov/pubmed/32057025
http://dx.doi.org/10.4103/ijo.IJO_1123_19
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author Ichhpujani, Parul
Kaushik, Sushmita
Gupta, Amit
Pandav, Surinder S
author_facet Ichhpujani, Parul
Kaushik, Sushmita
Gupta, Amit
Pandav, Surinder S
author_sort Ichhpujani, Parul
collection PubMed
description A 22-year-old female presented with bilateral, progressive diminution of vision. Slit-lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad-based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM), a membrane extending from corneal endothelium to anterior iris surface causing traction was seen. Confocal microscopy showed an “epithelium-like” transformation of the corneal endothelium. This case demonstrates a bilateral Chandler variant of the iridocorneal endothelial (ICE) syndrome where the diagnosis of Chandler's disease was confirmed by confocal microscopy, after the mechanism of secondary angle closure was demonstrated by the UBM.
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spelling pubmed-70431712020-03-13 Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy Ichhpujani, Parul Kaushik, Sushmita Gupta, Amit Pandav, Surinder S Indian J Ophthalmol Case Reports A 22-year-old female presented with bilateral, progressive diminution of vision. Slit-lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad-based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM), a membrane extending from corneal endothelium to anterior iris surface causing traction was seen. Confocal microscopy showed an “epithelium-like” transformation of the corneal endothelium. This case demonstrates a bilateral Chandler variant of the iridocorneal endothelial (ICE) syndrome where the diagnosis of Chandler's disease was confirmed by confocal microscopy, after the mechanism of secondary angle closure was demonstrated by the UBM. Wolters Kluwer - Medknow 2020-03 2020-02-14 /pmc/articles/PMC7043171/ /pubmed/32057025 http://dx.doi.org/10.4103/ijo.IJO_1123_19 Text en Copyright: © 2020 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Ichhpujani, Parul
Kaushik, Sushmita
Gupta, Amit
Pandav, Surinder S
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_full Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_fullStr Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_full_unstemmed Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_short Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_sort bilateral chandler's syndrome: uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043171/
https://www.ncbi.nlm.nih.gov/pubmed/32057025
http://dx.doi.org/10.4103/ijo.IJO_1123_19
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