Cargando…
Differential activation of G protein‐mediated signaling by synthetic cannabinoid receptor agonists
Synthetic cannabinoid receptor agonists (SCRAs) are new psychoactive substances associated with acute intoxication and even death. However, the molecular mechanisms through which SCRAs may exert their toxic effects remain unclear—including the potential differential activation of G protein subtypes...
Autores principales: | Sachdev, Shivani, Banister, Samuel D., Santiago, Marina, Bladen, Chris, Kassiou, Michael, Connor, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043210/ https://www.ncbi.nlm.nih.gov/pubmed/32101383 http://dx.doi.org/10.1002/prp2.566 |
Ejemplares similares
-
Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB(2)
receptor
por: Patel, Monica, et al.
Publicado: (2023) -
CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist
por: Kevin, Richard C., et al.
Publicado: (2019) -
The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities
por: Longworth, Mitchell, et al.
Publicado: (2016) -
Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells
por: Sachdev, Shivani, et al.
Publicado: (2019) -
Off-target pharmacological profiling of synthetic cannabinoid receptor agonists including AMB-FUBINACA, CUMYL-PINACA, PB-22, and XLR-11
por: Kevin, Richard C., et al.
Publicado: (2022)