Cargando…
STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy
The JAK-STAT signalling pathway regulates cellular processes like cell division, cell death and immune regulation. Dysregulation has been identified in solid tumours and STAT3 activation is a marker for poor outcome. The aim of this study was to explore potential therapeutic strategies by targeting...
Autores principales: | Hindupur, Sruthi V., Schmid, Sebastian C., Koch, Jana Annika, Youssef, Ahmed, Baur, Eva-Maria, Wang, Dongbiao, Horn, Thomas, Slotta-Huspenina, Julia, Gschwend, Juergen E., Holm, Per Sonne, Nawroth, Roman |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043223/ https://www.ncbi.nlm.nih.gov/pubmed/32046095 http://dx.doi.org/10.3390/ijms21031106 |
Ejemplares similares
-
Concepts in Oncolytic Adenovirus Therapy
por: Mantwill, Klaus, et al.
Publicado: (2021) -
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus
por: Koch, Jana, et al.
Publicado: (2022) -
Functional genomics identifies predictive markers and clinically actionable resistance mechanisms to CDK4/6 inhibition in bladder cancer
por: Tong, Zhichao, et al.
Publicado: (2019) -
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
por: Mantwill, Klaus, et al.
Publicado: (2013) -
Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice
por: El-Ayoubi, Ali, et al.
Publicado: (2023)