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Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons

Neurological diseases constitute a quarter of global disease burden and are expected to rise worldwide with the ageing of human populations. There is an increasing need to develop new molecular systems which can deliver drugs specifically into neurons, non-dividing cells meant to last a human lifeti...

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Detalles Bibliográficos
Autores principales: Leese, Charlotte, Bresnahan, Rebecca, Doran, Ciara, Simsek, Deniz, Fellows, Alexander D., Restani, Laura, Caleo, Matteo, Schiavo, Giampietro, Mavlyutov, Timur, Henke, Tina, Binz, Thomas, Davletov, Bazbek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043326/
https://www.ncbi.nlm.nih.gov/pubmed/32140681
http://dx.doi.org/10.1016/j.toxcx.2019.100019