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Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons
Neurological diseases constitute a quarter of global disease burden and are expected to rise worldwide with the ageing of human populations. There is an increasing need to develop new molecular systems which can deliver drugs specifically into neurons, non-dividing cells meant to last a human lifeti...
Autores principales: | Leese, Charlotte, Bresnahan, Rebecca, Doran, Ciara, Simsek, Deniz, Fellows, Alexander D., Restani, Laura, Caleo, Matteo, Schiavo, Giampietro, Mavlyutov, Timur, Henke, Tina, Binz, Thomas, Davletov, Bazbek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043326/ https://www.ncbi.nlm.nih.gov/pubmed/32140681 http://dx.doi.org/10.1016/j.toxcx.2019.100019 |
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