Cargando…

Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients

BACKGROUND: The aim of this study was to determine the risk factors and develop a nomogram for blood transfusions after hemiarthroplasty (HA) in patients with femoral neck fractures (FNFs). MATERIAL/METHODS: We performed a retrospective study including consecutive elderly FNF patients treated by HA...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ji-Qi, Chen, Lu-Ying, Jiang, Bing-Jie, Zhao, You-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043352/
https://www.ncbi.nlm.nih.gov/pubmed/32074099
http://dx.doi.org/10.12659/MSM.920255
_version_ 1783501431198711808
author Wang, Ji-Qi
Chen, Lu-Ying
Jiang, Bing-Jie
Zhao, You-Ming
author_facet Wang, Ji-Qi
Chen, Lu-Ying
Jiang, Bing-Jie
Zhao, You-Ming
author_sort Wang, Ji-Qi
collection PubMed
description BACKGROUND: The aim of this study was to determine the risk factors and develop a nomogram for blood transfusions after hemiarthroplasty (HA) in patients with femoral neck fractures (FNFs). MATERIAL/METHODS: We performed a retrospective study including consecutive elderly FNF patients treated by HA between January 2015 and December 2017. Perioperative information was obtained retrospectively, uni- and multivariate regression analyses were conducted to determine risk factors for blood transfusion, and a nomogram model was constructed to predict the risk of blood transfusion. The predictive performance and consistency of the model were evaluated by the consistency coefficient (C-index) and the calibration curve, respectively. RESULTS: Of 178 patients, 151 were finally enrolled in the study and 21 received blood transfusion. Binary logistic regression analysis showed the low preoperative hemoglobin (Hb), longer time to surgery, general anesthesia, longer surgery duration, and higher intraoperative blood loss (IBL) were risk factors for blood transfusion. The accuracy of the contour map for predicting transfusion risk was 0.940. CONCLUSIONS: We found a correlation between blood transfusion requirement and low preoperative Hb, longer time to surgery, general anesthesia, longer surgery duration, and higher IBL, and we then developed a nomogram. Our nomogram model can be used to evaluate the transfusion risk for FNF patients after HA, and provides better guidance for clinicians to intervene perioperatively, so as to reduce the incidence of blood transfusion.
format Online
Article
Text
id pubmed-7043352
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher International Scientific Literature, Inc.
record_format MEDLINE/PubMed
spelling pubmed-70433522020-03-13 Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients Wang, Ji-Qi Chen, Lu-Ying Jiang, Bing-Jie Zhao, You-Ming Med Sci Monit Clinical Research BACKGROUND: The aim of this study was to determine the risk factors and develop a nomogram for blood transfusions after hemiarthroplasty (HA) in patients with femoral neck fractures (FNFs). MATERIAL/METHODS: We performed a retrospective study including consecutive elderly FNF patients treated by HA between January 2015 and December 2017. Perioperative information was obtained retrospectively, uni- and multivariate regression analyses were conducted to determine risk factors for blood transfusion, and a nomogram model was constructed to predict the risk of blood transfusion. The predictive performance and consistency of the model were evaluated by the consistency coefficient (C-index) and the calibration curve, respectively. RESULTS: Of 178 patients, 151 were finally enrolled in the study and 21 received blood transfusion. Binary logistic regression analysis showed the low preoperative hemoglobin (Hb), longer time to surgery, general anesthesia, longer surgery duration, and higher intraoperative blood loss (IBL) were risk factors for blood transfusion. The accuracy of the contour map for predicting transfusion risk was 0.940. CONCLUSIONS: We found a correlation between blood transfusion requirement and low preoperative Hb, longer time to surgery, general anesthesia, longer surgery duration, and higher IBL, and we then developed a nomogram. Our nomogram model can be used to evaluate the transfusion risk for FNF patients after HA, and provides better guidance for clinicians to intervene perioperatively, so as to reduce the incidence of blood transfusion. International Scientific Literature, Inc. 2020-02-19 /pmc/articles/PMC7043352/ /pubmed/32074099 http://dx.doi.org/10.12659/MSM.920255 Text en © Med Sci Monit, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Wang, Ji-Qi
Chen, Lu-Ying
Jiang, Bing-Jie
Zhao, You-Ming
Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients
title Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients
title_full Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients
title_fullStr Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients
title_full_unstemmed Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients
title_short Development of a Nomogram for Predicting Blood Transfusion Risk After Hemiarthroplasty for Femoral Neck Fractures in Elderly Patients
title_sort development of a nomogram for predicting blood transfusion risk after hemiarthroplasty for femoral neck fractures in elderly patients
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043352/
https://www.ncbi.nlm.nih.gov/pubmed/32074099
http://dx.doi.org/10.12659/MSM.920255
work_keys_str_mv AT wangjiqi developmentofanomogramforpredictingbloodtransfusionriskafterhemiarthroplastyforfemoralneckfracturesinelderlypatients
AT chenluying developmentofanomogramforpredictingbloodtransfusionriskafterhemiarthroplastyforfemoralneckfracturesinelderlypatients
AT jiangbingjie developmentofanomogramforpredictingbloodtransfusionriskafterhemiarthroplastyforfemoralneckfracturesinelderlypatients
AT zhaoyouming developmentofanomogramforpredictingbloodtransfusionriskafterhemiarthroplastyforfemoralneckfracturesinelderlypatients