MagnEdit—interacting factors that recruit DNA-editing enzymes to single base targets

Although CRISPR/Cas9 technology has created a renaissance in genome engineering, particularly for gene knockout generation, methods to introduce precise single base changes are also highly desirable. The covalent fusion of a DNA-editing enzyme such as APOBEC to a Cas9 nickase complex has heightened...

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Detalles Bibliográficos
Autores principales: McCann, Jennifer L, Salamango, Daniel J, Law, Emily K, Brown, William L, Harris, Reuben S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043409/
https://www.ncbi.nlm.nih.gov/pubmed/32094150
http://dx.doi.org/10.26508/lsa.201900606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043409/
https://www.ncbi.nlm.nih.gov/pubmed/32094150
http://dx.doi.org/10.26508/lsa.201900606

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