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A C-terminal peptide from type I interferon protects the retina in a mouse model of autoimmune uveitis

Experimental autoimmune uveitis (EAU) in rodents recapitulates many features of the disease in humans and has served as a useful tool for the development of therapeutics. A peptide from C-terminus of interferon α1, conjugated to palmitoyl-lysine for cell penetration, denoted as IFNα-C, was tested fo...

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Detalles Bibliográficos
Autores principales: Ahmed, Chulbul M., Ildefonso, Cristhian J., Johnson, Howard M., Lewin, Alfred S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043762/
https://www.ncbi.nlm.nih.gov/pubmed/32101556
http://dx.doi.org/10.1371/journal.pone.0227524