Cargando…
Evaluation of machine learning models for automatic detection of DNA double strand breaks after irradiation using a γH2AX foci assay
Ionizing radiation induces amongst other the most critical type of DNA damage: double-strand breaks (DSBs). Efficient repair of such damage is crucial for cell survival and genomic stability. The analysis of DSB associated foci assays is often performed manually or with automatic systems. Manual eva...
Autores principales: | Hohmann, Tim, Kessler, Jacqueline, Vordermark, Dirk, Dehghani, Faramarz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043763/ https://www.ncbi.nlm.nih.gov/pubmed/32101565 http://dx.doi.org/10.1371/journal.pone.0229620 |
Ejemplares similares
-
Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced γH2A.X Foci
por: Markunas, Christina A., et al.
Publicado: (2008) -
γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
por: Kinner, Andrea, et al.
Publicado: (2008) -
Calibration of the γ-H2AX DNA Double Strand Break Focus Assay for Internal Radiation Exposure of Blood Lymphocytes
por: Eberlein, Uta, et al.
Publicado: (2015) -
An Analytical Method for Quantifying the Yields of DNA Double-Strand Breaks Coupled with Strand Breaks by γ-H2AX Focus Formation Assay Based on Track-Structure Simulation
por: Yachi, Yoshie, et al.
Publicado: (2023) -
Multispectral imaging flow cytometry reveals distinct frequencies of γ-H2AX foci induction in DNA double strand break repair defective human cell lines
por: Bourton, Emma C, et al.
Publicado: (2012)