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Evaluation of machine learning models for automatic detection of DNA double strand breaks after irradiation using a γH2AX foci assay

Ionizing radiation induces amongst other the most critical type of DNA damage: double-strand breaks (DSBs). Efficient repair of such damage is crucial for cell survival and genomic stability. The analysis of DSB associated foci assays is often performed manually or with automatic systems. Manual eva...

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Detalles Bibliográficos
Autores principales: Hohmann, Tim, Kessler, Jacqueline, Vordermark, Dirk, Dehghani, Faramarz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043763/
https://www.ncbi.nlm.nih.gov/pubmed/32101565
http://dx.doi.org/10.1371/journal.pone.0229620

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