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Herpes simplex virus type 1 inflammasome activation in proinflammatory human macrophages is dependent on NLRP3, ASC, and caspase-1

The proinflammatory cytokines interleukin (IL)-1β and IL-18 are products of activation of the inflammasome, an innate sensing system, and important in the pathogenesis of herpes simplex virus type 1 (HSV-1). The release of IL-18 and IL-1β from monocytes/macrophages is critical for protection from HS...

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Detalles Bibliográficos
Autores principales:	Karaba, Andrew H., Figueroa, Alexis, Massaccesi, Guido, Botto, Sara, DeFilippis, Victor R., Cox, Andrea L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043765/ https://www.ncbi.nlm.nih.gov/pubmed/32101570 http://dx.doi.org/10.1371/journal.pone.0229570

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