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HIV protease cleaves the antiviral m(6)A reader protein YTHDF3 in the viral particle

N(6)-methyladenosine (m(6)A) is the most abundant HIV RNA modification but the interplay between the m(6)A reader protein YTHDF3 and HIV replication is not well understood. We found that knockout of YTHDF3 in human CD4+ T-cells increases infection supporting the role of YTHDF3 as a restriction facto...

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Detalles Bibliográficos
Autores principales:	Jurczyszak, Denise, Zhang, Wen, Terry, Sandra N., Kehrer, Thomas, Bermúdez González, Maria C., McGregor, Emma, Mulder, Lubbertus C. F., Eckwahl, Matthew J., Pan, Tao, Simon, Viviana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043784/ https://www.ncbi.nlm.nih.gov/pubmed/32053707 http://dx.doi.org/10.1371/journal.ppat.1008305

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