Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2

Malaria parasites suppress host immune responses to facilitate their survival, but the underlying mechanism remains elusive. Here, we found that blood-stage malaria parasites predominantly induced CD4(+)Foxp3(+)CD25(+) regulatory T cells to release soluble fibrinogen-like protein 2 (sFGL2), which su...

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Detalles Bibliográficos
Autores principales: Fu, Yong, Ding, Yan, Wang, Qinghui, Zhu, Feng, Tan, Yulong, Lu, Xiao, Guo, Bo, Zhang, Qingfeng, Cao, Yaming, Liu, Taiping, Cui, Liwang, Xu, Wenyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043914/
https://www.ncbi.nlm.nih.gov/pubmed/32133407
http://dx.doi.org/10.1126/sciadv.aay9269

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