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Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression

Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis induced by chemical stimuli, we studied its effect and possible...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Deng, Qing-Hua, Deng, Jian-Hua, Wang, Sheng-Ju, Chen, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043998/
https://www.ncbi.nlm.nih.gov/pubmed/32140037
http://dx.doi.org/10.4196/kjpp.2020.24.2.137