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Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression
Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis induced by chemical stimuli, we studied its effect and possible...
Autores principales: | Zhang, Xu, Deng, Qing-Hua, Deng, Jian-Hua, Wang, Sheng-Ju, Chen, Qiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043998/ https://www.ncbi.nlm.nih.gov/pubmed/32140037 http://dx.doi.org/10.4196/kjpp.2020.24.2.137 |
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