Cargando…

Gestational high fat diet protects 3xTg offspring from memory impairments, synaptic dysfunction and brain pathology

Maternal history for sporadic Alzheimer’s disease (AD) predisposes the offspring to the disease later in life. However, the mechanisms behind this phenomenon are still unknown. Lifestyle and nutrition can directly modulate susceptibility to AD. Herein we investigated whether gestational high fat die...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Meco, Antonio, Jelinek, Jaroslav, Lauretti, Elisabetta, Curtis, Mary Elizabeth, Issa, Jean-Pierre J., Praticό, Domenico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044032/ https://www.ncbi.nlm.nih.gov/pubmed/31451749 http://dx.doi.org/10.1038/s41380-019-0489-y

Ejemplares similares

Reply to comment: Extravirgin olive oil ameliorates cognition and neuropathology of the 3xTg mice
por: Lauretti, Elisabetta, et al.
Publicado: (2017)

Extra‐virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy
por: Lauretti, Elisabetta, et al.
Publicado: (2017)

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
por: Van der Jeugd, Ann, et al.
Publicado: (2018)

Fingolimod Rescues Memory and Improves Pathological Hallmarks in the 3xTg-AD Model of Alzheimer’s Disease
por: Fagan, Steven G., et al.
Publicado: (2022)

Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model
por: Kang, Shinwoo, et al.
Publicado: (2021)

Hypertension Accelerates Alzheimer’s Disease-Related Pathologies in Pigs and 3xTg Mice
por: Shih, Yao-Hsiang, et al.
Publicado: (2018)

Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Mice
por: Stojakovic, Andrea, et al.
Publicado: (2021)

IVIg protects the 3xTg-AD mouse model of Alzheimer’s disease from memory deficit and Aβ pathology
por: St-Amour, Isabelle, et al.
Publicado: (2014)

Olfactory dysfunction in the 3xTg-AD model of Alzheimer’s disease
por: Mitrano, Darlene A., et al.
Publicado: (2021)

Age-Dependent Decline in Synaptic Mitochondrial Function Is Exacerbated in Vulnerable Brain Regions of Female 3xTg-AD Mice
por: Espino de la Fuente-Muñoz, César, et al.
Publicado: (2020)

Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer’s disease mouse model promotes synaptic resilience
por: Bourne, Krystyn Z., et al.
Publicado: (2019)

Mesenchymal Stem Cells Preserve Working Memory in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Ruzicka, Jiri, et al.
Publicado: (2016)

Attenuation of HECT-E3 ligase expression rescued memory deficits in 3xTg-AD mice
por: Suresh, Pavithra, et al.
Publicado: (2022)

Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice
por: Belfiore, Ramona, et al.
Publicado: (2018)

Effects of Dietary Supplementation of Carnosine on Mitochondrial Dysfunction, Amyloid Pathology, and Cognitive Deficits in 3xTg-AD Mice
por: Corona, Carlo, et al.
Publicado: (2011)

Dopaminergic dysfunction in the 3xTg-AD mice model of Alzheimer’s disease
por: Gloria, Yesica, et al.
Publicado: (2021)

Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer’s disease pathology in TgSwDI and 3xTg mouse models
por: Goñi, Fernando, et al.
Publicado: (2013)

Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer’s disease
por: Robison, Lisa S., et al.
Publicado: (2020)

Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model
por: Lauretti, E, et al.
Publicado: (2017)

Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice
por: Giménez-Llort, Lydia, et al.
Publicado: (2010)

Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Stimmell, Alina C., et al.
Publicado: (2019)

Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer’s Disease
por: Dionisio-Santos, Dawling A., et al.
Publicado: (2020)

Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Javonillo, Dominic I., et al.
Publicado: (2022)

Abnormal whisker movements in the 3xTg‐AD mouse model of Alzheimer's disease
por: Simanaviciute, Ugne, et al.
Publicado: (2022)

Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer’s disease
por: Liu, Yubing, et al.
Publicado: (2023)

Neuroprotective Effect of Nosustrophine in a 3xTg Mouse Model of Alzheimer’s Disease
por: Carrera, Iván, et al.
Publicado: (2023)

BACE1 RNAi Restores the Composition of Phosphatidylethanolamine-Derivates Related to Memory Improvement in Aged 3xTg-AD Mice
por: Villamil-Ortiz, Javier G., et al.
Publicado: (2016)

Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice
por: Liu, Yinghua, et al.
Publicado: (2019)

Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD Mice
por: Fernandes, Adelaide, et al.
Publicado: (2022)

The Effects of Physical Running on Dendritic Spines and Amyloid-beta Pathology in 3xTg-AD Male Mice
por: Xu, Benke, et al.
Publicado: (2022)

Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer’s disease pathology
por: Chen, Lingxuan, et al.
Publicado: (2023)

Sex-Specific Effects of High Fat Diet on Indices of Metabolic Syndrome in 3xTg-AD Mice: Implications for Alzheimer's Disease
por: Barron, Anna M., et al.
Publicado: (2013)

Liver and White/Brown Fat Dystrophy Associates with Gut Microbiota and Metabolomic Alterations in 3xTg Alzheimer’s Disease Mouse Model
por: Guzzardi, Maria Angela, et al.
Publicado: (2022)

RAPGEF2 mediates oligomeric Aβ‐induced synaptic loss and cognitive dysfunction in the 3xTg‐AD mouse model of Alzheimer’s disease
por: Jang, You‐Na, et al.
Publicado: (2021)

Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice
por: Chen, Yanxing, et al.
Publicado: (2014)

Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice
por: Djordjevic, Jelena, et al.
Publicado: (2020)

Alterations of the Sympathoadrenal Axis Related to the Development of Alzheimer’s Disease in the 3xTg Mouse Model
por: Muñoz-Montero, Alicia, et al.
Publicado: (2022)

Neuroprotective Effects of Probiotic-Supplemented Diet on Cognitive Behavior of 3xTg-AD Mice
por: Tan, Chenxi, et al.
Publicado: (2022)

Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Jullienne, Amandine, et al.
Publicado: (2022)

Alterations in Retinal Signaling Across Age and Sex in 3xTg Alzheimer’s Disease Mice
por: Frame, Gabrielle, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jvrn9jr55sejdsir2tu9lc3o08