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Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina

Tetrahydrobiopterin (BH(4)) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its exact role in lipogenesis is unclear. In this study, the GTP cyclohydrolase I (GTPCH) gene was overexpressed to investigate the role of BH(4) in lipogenesis in oleagino...

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Detalles Bibliográficos
Autores principales:	Wang, Hongchao, Zhang, Chen, Chen, Haiqin, Gu, Zhennan, Zhao, Jianxin, Zhang, Hao, Chen, Yong Q., Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044132/ https://www.ncbi.nlm.nih.gov/pubmed/32153536 http://dx.doi.org/10.3389/fmicb.2020.00250

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