Cargando…

Leishmania donovani infection induce differential miRNA expression in CD4+ T cells

Visceral leishmaniasis is characterized by mixed production of Th1/2 cytokines and the disease is established by an enhanced level of Th2 cytokine. CD4+ T cells are main cell type which produces Th1/2 cytokine in the host upon Leishmania infection. However, the regulatory mechanism for Th1/2 product...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Vinod, Das, Sushmita, Kumar, Ajay, Tiwari, Neeraj, Kumar, Ashish, Abhishek, Kumar, Mandal, Abhishek, Kumar, Manjay, Shafi, Taj, Bamra, Tanvir, Singh, Rakesh Kumar, Vijayakumar, Saravanan, Sen, Abhik, Das, Pradeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044172/ https://www.ncbi.nlm.nih.gov/pubmed/32103111 http://dx.doi.org/10.1038/s41598-020-60435-2

Ejemplares similares

Leishmania donovani Secretory Mevalonate Kinase Regulates Host Immune Response and Facilitates Phagocytosis
por: Bamra, Tanvir, et al.
Publicado: (2021)

Leishmania donovani induced Unfolded Protein Response delays host cell apoptosis in PERK dependent manner
por: Abhishek, Kumar, et al.
Publicado: (2018)

Leishmania donovani Activates Hypoxia Inducible Factor-1α and miR-210 for Survival in Macrophages by Downregulation of NF-κB Mediated Pro-inflammatory Immune Response
por: Kumar, Vinod, et al.
Publicado: (2018)

Differential Regulation of miRNA Profiles of Human Cells Experimentally Infected by Leishmania donovani Isolated From Indian Visceral Leishmaniasis and Post-Kala-Azar Dermal Leishmaniasis
por: Kumar, Ashish, et al.
Publicado: (2020)

Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host
por: Verma, Sudha, et al.
Publicado: (2018)

Genetic Manipulation of Leishmania donovani to Explore the Involvement of Argininosuccinate Synthase in Oxidative Stress Management
por: Sardar, Abul Hasan, et al.
Publicado: (2016)

Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b
por: Singh, Ruby, et al.
Publicado: (2016)

Deprivation of L-Arginine Induces Oxidative Stress Mediated Apoptosis in Leishmania donovani Promastigotes: Contribution of the Polyamine Pathway
por: Mandal, Abhishek, et al.
Publicado: (2016)

Retraction Note to: Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b
por: Singh, Ruby, et al.
Publicado: (2022)

l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis
por: Mandal, Abhishek, et al.
Publicado: (2017)

Corrigendum: l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis
por: Mandal, Abhishek, et al.
Publicado: (2020)

Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut
por: Verma, Sudha, et al.
Publicado: (2017)

Retraction Note: Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut
por: Verma, Sudha, et al.
Publicado: (2023)

TLR4 and TLR9 polymorphism: Probable role in susceptibility among the population of Bihar for Indian visceral leishmaniasis
por: Mandal, Abhishek, et al.
Publicado: (2021)

RETRACTED ARTICLE: Nucleic acid sensing activates the innate cytosolic surveillance pathway and promotes parasite survival in visceral leishmaniasis
por: Das, Sushmita, et al.
Publicado: (2019)

Retraction Note: Nucleic acid sensing activates the innate cytosolic surveillance pathway and promotes parasite survival in visceral leishmaniasis
por: Das, Sushmita, et al.
Publicado: (2022)

Identification and Characterization of miRNAs in Response to Leishmania donovani Infection: Delineation of Their Roles in Macrophage Dysfunction
por: Tiwari, Neeraj, et al.
Publicado: (2017)

Activity of a novel sulfonamide compound 2-nitro-N-(pyridin-2-ylmethyl)benzenesulfonamide against Leishmania donovani
por: Dikhit, Manas R, et al.
Publicado: (2016)

Corrigendum: Identification and Characterization of miRNAs in Response to Leishmania donovani Infection: Delineation of Their Roles in Macrophage Dysfunction
por: Tiwari, Neeraj, et al.
Publicado: (2017)

Oxidative Stress-Mediated Overexpression of Uracil DNA Glycosylase in Leishmania donovani Confers Tolerance against Antileishmanial Drugs
por: Mishra, Anshul, et al.
Publicado: (2018)

In silico screening, molecular dynamic simulations, and in vitro activity of selected natural compounds as an inhibitor of Leishmania donovani 3-mercaptopyruvate sulfurtransferase
por: Kant, Vishnu, et al.
Publicado: (2022)

The potential HLA Class I-restricted epitopes derived from LeIF and TSA of Leishmania donovani evoke anti-leishmania CD8+ T lymphocyte response
por: Dikhit, Manas Ranjan, et al.
Publicado: (2018)

Intracellular zinc flux causes reactive oxygen species mediated mitochondrial dysfunction leading to cell death in Leishmania donovani
por: Kumari, Anjali, et al.
Publicado: (2017)

Leishmania donovani infection activates Toll-like receptor 2, 4 expressions and Transforming growth factor-beta mediated apoptosis in renal tissues
por: Kumar, Vinod, et al.
Publicado: (2017)

Molecular Epidemiology of Extended-Spectrum β-Lactamase–Producing Escherichia coli Pathotypes in Diarrheal Children from Low Socioeconomic Status Communities in Bihar, India: Emergence of the CTX-M Type
por: Mandal, Abhishek, et al.
Publicado: (2017)

Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani
por: Kumar, Ritesh, et al.
Publicado: (2017)

Livestock and rodents within an endemic focus of Visceral Leishmaniasis are not reservoir hosts for Leishmania donovani
por: Kushwaha, Anurag Kumar, et al.
Publicado: (2022)

Leishmania donovani Internalizes into Host Cells via Caveolin-mediated Endocytosis
por: Kumar, G. Aditya, et al.
Publicado: (2019)

RNA-Seq Revealed Expression of Many Novel Genes Associated With Leishmania donovani Persistence and Clearance in the Host Macrophage
por: Shadab, Mohammad, et al.
Publicado: (2019)

Identification of Leishmania donovani antigen in circulating immune complexes of visceral leishmaniasis subjects for diagnosis
por: Jamal, Fauzia, et al.
Publicado: (2017)

Identification of Potential MHC Class-II-Restricted Epitopes Derived from Leishmania donovani Antigens by Reverse Vaccinology and Evaluation of Their CD4+ T-Cell Responsiveness against Visceral Leishmaniasis
por: Dikhit, Manas Ranjan, et al.
Publicado: (2017)

Identification and Functional Characterization of Leishmania donovani Secretory Peroxidase: Delineating Its Role in NRAMP1 Regulation
por: Singh, Nisha, et al.
Publicado: (2013)

Visceral Leishmaniasis Caused by Leishmania donovani Zymodeme MON-37, Western Ghats, India
por: Saini, Prasanta, et al.
Publicado: (2020)

Quantitative Proteome Analysis of Leishmania donovani under Spermidine Starvation
por: Singh, Shalini, et al.
Publicado: (2016)

Mechanistic insight into the role of mevalonate kinase by a natural fatty acid-mediated killing of Leishmania donovani
por: Prasad, Surendra Rajit, et al.
Publicado: (2022)

Genomic and Transcriptomic Analysis for Identification of Genes and Interlinked Pathways Mediating Artemisinin Resistance in Leishmania donovani
por: Ghosh, Sushmita, et al.
Publicado: (2020)

Latent Infection with Leishmania donovani in Highly Endemic Villages in Bihar, India
por: Hasker, Epco, et al.
Publicado: (2013)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Comparative in-silico genome analysis of Leishmania (Leishmania) donovani: A step towards its species specificity
por: S., Satheesh Kumar, et al.
Publicado: (2014)

Thromboangiitis Obliterans (Buerger's Disease)—Current Practices
por: Vijayakumar, Abhishek, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_frdkkqo3qf73j59t5glunbhme5