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The Variable Genomic NK Cell Receptor Locus Is a Key Determinant of CD4+ T Cell Responses During Viral Infection

Increasing evidence points to a key role for NK cells in controlling adaptive immune responses. In studies examining the role of CD1d on CD4+ T cell responses, we found that a line of CD1d-deficient mice on the C57BL/6J background had a homozygous 129 locus on chromosome 6 containing the entire NK c...

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Detalles Bibliográficos
Autores principales:	Raynor, Jana, Lin, Adora, Hummel, Sarah A., Lampe, Kristin, Jordan, Michael, Hoebe, Kasper, Hildeman, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044186/ https://www.ncbi.nlm.nih.gov/pubmed/32153566 http://dx.doi.org/10.3389/fimmu.2020.00197

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