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Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism
Depression is one of the most common disorders causing mortality around the world. Although electroconvulsive therapy (ECT) is, along with antidepressants and psychotherapy, one of the three major treatments of depression, it is still considered as the last resort for depressed patients. This situat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044268/ https://www.ncbi.nlm.nih.gov/pubmed/32153449 http://dx.doi.org/10.3389/fpsyg.2020.00080 |
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author | Li, Ming Yao, Xiaoxiao Sun, Lihua Zhao, Lihong Xu, Wenbo Zhao, Haisheng Zhao, Fangyi Zou, Xiaohan Cheng, Ziqian Li, Bingjin Yang, Wei Cui, Ranji |
author_facet | Li, Ming Yao, Xiaoxiao Sun, Lihua Zhao, Lihong Xu, Wenbo Zhao, Haisheng Zhao, Fangyi Zou, Xiaohan Cheng, Ziqian Li, Bingjin Yang, Wei Cui, Ranji |
author_sort | Li, Ming |
collection | PubMed |
description | Depression is one of the most common disorders causing mortality around the world. Although electroconvulsive therapy (ECT) is, along with antidepressants and psychotherapy, one of the three major treatments of depression, it is still considered as the last resort for depressed patients. This situation is partially due to limited studies and uncertainty regarding its mechanism. However, decades of increased research have focused on the effects of ECT on depression and its potential mechanism. Furthermore, these investigations may suggest that ECT should be a first-line therapy for depression due to its profound effects in relieving desperation in certain situations. Here, we outline recent clinical and preclinical studies and summarize the advantages and disadvantages of ECT. Thus, this review may provide some hints for clinical application. |
format | Online Article Text |
id | pubmed-7044268 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70442682020-03-09 Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism Li, Ming Yao, Xiaoxiao Sun, Lihua Zhao, Lihong Xu, Wenbo Zhao, Haisheng Zhao, Fangyi Zou, Xiaohan Cheng, Ziqian Li, Bingjin Yang, Wei Cui, Ranji Front Psychol Psychology Depression is one of the most common disorders causing mortality around the world. Although electroconvulsive therapy (ECT) is, along with antidepressants and psychotherapy, one of the three major treatments of depression, it is still considered as the last resort for depressed patients. This situation is partially due to limited studies and uncertainty regarding its mechanism. However, decades of increased research have focused on the effects of ECT on depression and its potential mechanism. Furthermore, these investigations may suggest that ECT should be a first-line therapy for depression due to its profound effects in relieving desperation in certain situations. Here, we outline recent clinical and preclinical studies and summarize the advantages and disadvantages of ECT. Thus, this review may provide some hints for clinical application. Frontiers Media S.A. 2020-02-20 /pmc/articles/PMC7044268/ /pubmed/32153449 http://dx.doi.org/10.3389/fpsyg.2020.00080 Text en Copyright © 2020 Li, Yao, Sun, Zhao, Xu, Zhao, Zhao, Zou, Cheng, Li, Yang and Cui. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychology Li, Ming Yao, Xiaoxiao Sun, Lihua Zhao, Lihong Xu, Wenbo Zhao, Haisheng Zhao, Fangyi Zou, Xiaohan Cheng, Ziqian Li, Bingjin Yang, Wei Cui, Ranji Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism |
title | Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism |
title_full | Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism |
title_fullStr | Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism |
title_full_unstemmed | Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism |
title_short | Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism |
title_sort | effects of electroconvulsive therapy on depression and its potential mechanism |
topic | Psychology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044268/ https://www.ncbi.nlm.nih.gov/pubmed/32153449 http://dx.doi.org/10.3389/fpsyg.2020.00080 |
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