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Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry
Enzymatic digestion for protein sequencing usually requires much time, and does not always result in high sequence coverage. Here we report the use of aqueous microdroplets to accelerate enzymatic reactions and, in particular, to improve protein sequencing. When a room temperature aqueous solution c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044307/ https://www.ncbi.nlm.nih.gov/pubmed/32103000 http://dx.doi.org/10.1038/s41467-020-14877-x |