NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle

Lysine fatty acylation in mammalian cells was discovered nearly three decades ago, yet the enzymes catalyzing it remain unknown. Unexpectedly, we find that human N-terminal glycine myristoyltransferases (NMT) 1 and 2 can efficiently myristoylate specific lysine residues. They modify ADP-ribosylation...

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Detalles Bibliográficos
Autores principales: Kosciuk, Tatsiana, Price, Ian R., Zhang, Xiaoyu, Zhu, Chengliang, Johnson, Kayla N., Zhang, Shuai, Halaby, Steve L., Komaniecki, Garrison P., Yang, Min, DeHart, Caroline J., Thomas, Paul M., Kelleher, Neil L., Fromme, J. Christopher, Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044312/
https://www.ncbi.nlm.nih.gov/pubmed/32103017
http://dx.doi.org/10.1038/s41467-020-14893-x

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