c-FLIP is crucial for IL-7/IL-15-dependent NKp46(+) ILC development and protection from intestinal inflammation in mice

NKp46(+) innate lymphoid cells (ILC) modulate tissue homeostasis and anti-microbial immune responses. ILC development and function are regulated by cytokines such as Interleukin (IL)−7 and IL-15. However, the ILC-intrinsic pathways translating cytokine signals into developmental programs are largely...

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Detalles Bibliográficos
Autores principales: Bank, Ute, Deiser, Katrin, Plaza-Sirvent, Carlos, Osbelt, Lisa, Witte, Amelie, Knop, Laura, Labrenz, Rebecca, Jänsch, Robert, Richter, Felix, Biswas, Aindrila, Zenclussen, Ana C., Vivier, Eric, Romagnani, Chiara, Kühl, Anja A., Dunay, Ildiko R., Strowig, Till, Schmitz, Ingo, Schüler, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044440/
https://www.ncbi.nlm.nih.gov/pubmed/32103006
http://dx.doi.org/10.1038/s41467-020-14782-3

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