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Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway

The morbidity and mortality of primary liver cancer is one of the highest amongst all cancers. Deficiency of effective treatment and characteristics of cancer metastasis are believed to be responsible for this situation, thus a great demand is required for new agent development. Polyphyllin II (PP2)...

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Detalles Bibliográficos
Autores principales: Pang, Dejiang, Yang, Chengcheng, Li, Chao, Zou, Yuanfeng, Feng, Bin, Li, Lixia, Liu, Wentao, Luo, Qihui, Chen, Zhengli, Huang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044461/
https://www.ncbi.nlm.nih.gov/pubmed/31988091
http://dx.doi.org/10.1242/bio.046854