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Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway
The morbidity and mortality of primary liver cancer is one of the highest amongst all cancers. Deficiency of effective treatment and characteristics of cancer metastasis are believed to be responsible for this situation, thus a great demand is required for new agent development. Polyphyllin II (PP2)...
Autores principales: | Pang, Dejiang, Yang, Chengcheng, Li, Chao, Zou, Yuanfeng, Feng, Bin, Li, Lixia, Liu, Wentao, Luo, Qihui, Chen, Zhengli, Huang, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044461/ https://www.ncbi.nlm.nih.gov/pubmed/31988091 http://dx.doi.org/10.1242/bio.046854 |
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