DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging

BACKGROUND & AIMS: The epithelia of the intestine and colon turn over rapidly and are maintained by adult stem cells at the base of crypts. Although the small intestine and colon have distinct, well-characterized physiological functions, it remains unclear if there are fundamental regional diffe...

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Detalles Bibliográficos
Autores principales: Lewis, Sophia K., Nachun, Daniel, Martin, Martin G., Horvath, Steve, Coppola, Giovanni, Jones, D. Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044532/
https://www.ncbi.nlm.nih.gov/pubmed/31805439
http://dx.doi.org/10.1016/j.jcmgh.2019.11.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044532/
https://www.ncbi.nlm.nih.gov/pubmed/31805439
http://dx.doi.org/10.1016/j.jcmgh.2019.11.013

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