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DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging
BACKGROUND & AIMS: The epithelia of the intestine and colon turn over rapidly and are maintained by adult stem cells at the base of crypts. Although the small intestine and colon have distinct, well-characterized physiological functions, it remains unclear if there are fundamental regional diffe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044532/ https://www.ncbi.nlm.nih.gov/pubmed/31805439 http://dx.doi.org/10.1016/j.jcmgh.2019.11.013 |