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Effects of quercetin on antioxidant potential in the experimental periodontitis development

The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7(th) and 14(th) days of experimental periodontitis development both without correction and with the injection of a water-s...

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Autores principales: Demkovych, Andrii, Bondarenko, Yurii, Hasiuk, Petro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Akadémiai Kiadó 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044571/
https://www.ncbi.nlm.nih.gov/pubmed/32148904
http://dx.doi.org/10.1556/1646.11.2019.06
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author Demkovych, Andrii
Bondarenko, Yurii
Hasiuk, Petro
author_facet Demkovych, Andrii
Bondarenko, Yurii
Hasiuk, Petro
author_sort Demkovych, Andrii
collection PubMed
description The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7(th) and 14(th) days of experimental periodontitis development both without correction and with the injection of a water-soluble quercetin drug (corvitin). Hence, there was a decrease in superoxide dismutase activity, intensive increase in catalase activity, and ceruloplasmin maintenance in the blood serum during acute period of inflammatory process. The usage of flavonoid for 7  days resulted in stabilization of radical oxidation due to reduction of superoxide dismutase activity, maintenance at the high-level catalase activity, and ceruloplasmin concentration in the rat’s blood plasma with experimental bacterial-immune periodontitis.
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spelling pubmed-70445712020-03-06 Effects of quercetin on antioxidant potential in the experimental periodontitis development Demkovych, Andrii Bondarenko, Yurii Hasiuk, Petro Interv Med Appl Sci Original Paper The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7(th) and 14(th) days of experimental periodontitis development both without correction and with the injection of a water-soluble quercetin drug (corvitin). Hence, there was a decrease in superoxide dismutase activity, intensive increase in catalase activity, and ceruloplasmin maintenance in the blood serum during acute period of inflammatory process. The usage of flavonoid for 7  days resulted in stabilization of radical oxidation due to reduction of superoxide dismutase activity, maintenance at the high-level catalase activity, and ceruloplasmin concentration in the rat’s blood plasma with experimental bacterial-immune periodontitis. Akadémiai Kiadó 2019-03-26 2019-03 /pmc/articles/PMC7044571/ /pubmed/32148904 http://dx.doi.org/10.1556/1646.11.2019.06 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changes – if any – are indicated.
spellingShingle Original Paper
Demkovych, Andrii
Bondarenko, Yurii
Hasiuk, Petro
Effects of quercetin on antioxidant potential in the experimental periodontitis development
title Effects of quercetin on antioxidant potential in the experimental periodontitis development
title_full Effects of quercetin on antioxidant potential in the experimental periodontitis development
title_fullStr Effects of quercetin on antioxidant potential in the experimental periodontitis development
title_full_unstemmed Effects of quercetin on antioxidant potential in the experimental periodontitis development
title_short Effects of quercetin on antioxidant potential in the experimental periodontitis development
title_sort effects of quercetin on antioxidant potential in the experimental periodontitis development
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044571/
https://www.ncbi.nlm.nih.gov/pubmed/32148904
http://dx.doi.org/10.1556/1646.11.2019.06
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