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Effects of quercetin on antioxidant potential in the experimental periodontitis development
The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7(th) and 14(th) days of experimental periodontitis development both without correction and with the injection of a water-s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Akadémiai Kiadó
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044571/ https://www.ncbi.nlm.nih.gov/pubmed/32148904 http://dx.doi.org/10.1556/1646.11.2019.06 |
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author | Demkovych, Andrii Bondarenko, Yurii Hasiuk, Petro |
author_facet | Demkovych, Andrii Bondarenko, Yurii Hasiuk, Petro |
author_sort | Demkovych, Andrii |
collection | PubMed |
description | The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7(th) and 14(th) days of experimental periodontitis development both without correction and with the injection of a water-soluble quercetin drug (corvitin). Hence, there was a decrease in superoxide dismutase activity, intensive increase in catalase activity, and ceruloplasmin maintenance in the blood serum during acute period of inflammatory process. The usage of flavonoid for 7 days resulted in stabilization of radical oxidation due to reduction of superoxide dismutase activity, maintenance at the high-level catalase activity, and ceruloplasmin concentration in the rat’s blood plasma with experimental bacterial-immune periodontitis. |
format | Online Article Text |
id | pubmed-7044571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Akadémiai Kiadó |
record_format | MEDLINE/PubMed |
spelling | pubmed-70445712020-03-06 Effects of quercetin on antioxidant potential in the experimental periodontitis development Demkovych, Andrii Bondarenko, Yurii Hasiuk, Petro Interv Med Appl Sci Original Paper The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7(th) and 14(th) days of experimental periodontitis development both without correction and with the injection of a water-soluble quercetin drug (corvitin). Hence, there was a decrease in superoxide dismutase activity, intensive increase in catalase activity, and ceruloplasmin maintenance in the blood serum during acute period of inflammatory process. The usage of flavonoid for 7 days resulted in stabilization of radical oxidation due to reduction of superoxide dismutase activity, maintenance at the high-level catalase activity, and ceruloplasmin concentration in the rat’s blood plasma with experimental bacterial-immune periodontitis. Akadémiai Kiadó 2019-03-26 2019-03 /pmc/articles/PMC7044571/ /pubmed/32148904 http://dx.doi.org/10.1556/1646.11.2019.06 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changes – if any – are indicated. |
spellingShingle | Original Paper Demkovych, Andrii Bondarenko, Yurii Hasiuk, Petro Effects of quercetin on antioxidant potential in the experimental periodontitis development |
title | Effects of quercetin on antioxidant potential in the experimental periodontitis development |
title_full | Effects of quercetin on antioxidant potential in the experimental periodontitis development |
title_fullStr | Effects of quercetin on antioxidant potential in the experimental periodontitis development |
title_full_unstemmed | Effects of quercetin on antioxidant potential in the experimental periodontitis development |
title_short | Effects of quercetin on antioxidant potential in the experimental periodontitis development |
title_sort | effects of quercetin on antioxidant potential in the experimental periodontitis development |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044571/ https://www.ncbi.nlm.nih.gov/pubmed/32148904 http://dx.doi.org/10.1556/1646.11.2019.06 |
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