Cargando…

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

Constitutive activation of NF-κB is associated with proinflammatory diseases and suppression of the NF-κB signaling pathway has been considered as an effective therapeutic strategy in the treatment of various cancers including hepatocellular carcinoma (HCC). Herein, we report the synthesis of 1,2 ox...

Descripción completa

Detalles Bibliográficos
Autores principales: Somu, Chaithanya, Mohan, Chakrabhavi Dhananjaya, Ambekar, Sachin, Dukanya, Rangappa, Shobith, Baburajeev, CP, Sukhorukov, Alexey, Mishra, Srishti, Shanmugam, Muthu K, Chinnathambi, Arunachalam, Awad Alahmadi, Tahani, Alharbi, Sulaiman Ali, Basappa, Rangappa, Kanchugarakoppal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044713/
https://www.ncbi.nlm.nih.gov/pubmed/32140443
http://dx.doi.org/10.1016/j.btre.2020.e00438