Hybrid Spectral Library Combining DIA-MS Data and a Targeted Virtual Library Substantially Deepens the Proteome Coverage

Data-independent acquisition mass spectrometry (DIA-MS) is a powerful technique that enables relatively deep proteomic profiling with superior quantification reproducibility. DIA data mining predominantly relies on a spectral library of sufficient proteome coverage that, in most cases, is built on d...

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Detalles Bibliográficos
Autores principales: Lou, Ronghui, Tang, Pan, Ding, Kang, Li, Shanshan, Tian, Cuiping, Li, Yunxia, Zhao, Suwen, Zhang, Yaoyang, Shui, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044796/
https://www.ncbi.nlm.nih.gov/pubmed/32109675
http://dx.doi.org/10.1016/j.isci.2020.100903

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