Extensive Changes in Transcriptomic “Fingerprints” and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis

Background: Patients developing meningococcal septic shock reveal levels of Neisseria meningitidis (10(6)-10(8)/mL) and endotoxin (10(1)-10(3) EU/mL) in the circulation and organs, leading to acute cardiovascular, pulmonary and renal failure, coagulopathy and a high case fatality rate within 24 h. O...

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Detalles Bibliográficos
Autores principales: Brusletto, Berit Sletbakk, Løberg, Else Marit, Hellerud, Bernt Christian, Goverud, Ingeborg Løstegaard, Berg, Jens Petter, Olstad, Ole Kristoffer, Gopinathan, Unni, Brandtzaeg, Petter, Øvstebø, Reidun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045056/
https://www.ncbi.nlm.nih.gov/pubmed/32154187
http://dx.doi.org/10.3389/fcimb.2020.00042

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