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Dynamics Rationalize Proteolytic Susceptibility of the Major Birch Pollen Allergen Bet v 1

Proteolytic susceptibility during endolysosomal degradation is decisive for allergic sensitization. In the major birch pollen allergen Bet v 1 most protease cleavage sites are located within its secondary structure elements, which are inherently inaccessible to proteases. The allergen thus must unfo...

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Detalles Bibliográficos
Autores principales:	Kamenik, Anna S., Hofer, Florian, Handle, Philip H., Liedl, Klaus R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045072/ https://www.ncbi.nlm.nih.gov/pubmed/32154264 http://dx.doi.org/10.3389/fmolb.2020.00018

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